Lentiviral packaging constructs

Details Lentiviral packaging constructs Lentiviral packaging constructs

C - Chemistry, Metallurgy

12

N

C12N 15/86 (2006.01) C07K 14/155 (2006.01) C07K 14/16 (2006.01) C12N 5/10 (2006.01) C12N 15/49 (2006.01) C12N 15/867 (2006.01)

Patent

CA 2439067

The present invention provides novel lentiviral packaging constructs that are useful for the establishment of stable packaging cell lines and producer cell lines. In particular, the present invention provides novel packaging cell lines that are capable of constitutively expressing high levels of lentiviral proteins.

Cette invention concerne de nouveaux gènes hybrides d'encapsidation lentiviraux utiles pour la création de lignées d'encapsidation stables et de lignées de production. La présente invention concerne en particulier de nouvelles lignées d'encapsidation pouvant exprimer de manière constitutive d'importants niveaux de protéines lentivirales.

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