Leptomycin compounds

Details Leptomycin compounds Leptomycin compounds

A - Human Necessities

61

K

A61K 31/535 (2006.01) A61K 31/35 (2006.01) A61K 31/415 (2006.01) A61K 31/44 (2006.01) C07D 231/56 (2006.01) C07D 309/30 (2006.01) C07D 405/00 (2006.01) C07D 413/00 (2006.01)

Patent

CA 2568341

Leptomycin-type compounds according to formula I wherein R~, R1, R2, R10 R11 R12 R13R14, and m are as defined herein, exhibit anti-tumor activity.

Les composés de type leptomycine selon la formule I dans laquelle R?·¿, R?1¿, R?2¿, R?10 ¿R?11¿ R?12 ¿R?13¿R?14¿,? ¿et m sont tels que définis dans le présent document, présentent une activité antitumorale.

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