Lercanidipine free base

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 211/90 (2006.01)

Patent

CA 2597992

The invention provides substantially pure lercanidipine free base, having a purity of at least 95 %, preferably at least about 97 %, more preferably at least about 99 %, and still more preferably at least about 99.5 %. The lercanidipine free base of the present invention is formed as an amorphous solid that is easily handled and particularly well suited to the formulation of pharmaceutical compositions.

L'invention concerne une base libre de lercanidipine sensiblement pure, présentant une pureté d'au moins 95 %, de préférence d'au moins environ 97 %, préférablement d'au moins environ 99 %, et plus préférablement d'au moins environ 99,5 %. La base libre de lercanidipine de la présente invention se présente sous une forme solide amorphe facilement manipulable et particulièrement adaptée à la formulation de compositions pharmaceutiques.

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