C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A01K 67/027 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) C07K 14/705 (2006.01) C07K 14/72 (2006.01) C12N 5/10 (2006.01) C12N 15/62 (2006.01) C12N 15/86 (2006.01) C12Q 1/68 (2006.01) G01N 33/577 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2419491
The present invention provides Leucine-Rich Repeat-Containing G-Protein Coupled Receptor-8 (LGR8) polypeptides and nucleic acid molecules encoding the same. The invention also provides selective binding agents, vectors, host cells, and methods for producing LGR8 polypeptides. The invention further provides pharmaceutical compositions and methods for the diagnosis, treatment, amelioration, and/or prevention of diseases, disorders, and conditions associated with LGR8 polypeptides.
L'invention concerne des polypeptides du récepteur 8 (LGR8) couplé à la protéine G contenant des répétitions riches en leucines et elle concerne également des agents de liaison sélectifs, des vecteurs, cellules hôtes et procédés de production de tels polypeptides. L'invention concerne encore des compositions pharmaceutiques ainsi que des procédés de diagnostic, traitement, amélioration et/ou prévention de maladies, pathologies et états associés aux polypeptides LGR8.
Daugherty Betsy
Gong Jianhua
Paszty Christopher J.
Rogers Norma
Amgen Inc.
Gowling Lafleur Henderson Llp
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