Leukaemia inhibitory factor-binding protein

Details Leukaemia inhibitory factor-binding protein Leukaemia inhibitory factor-binding protein

C - Chemistry, Metallurgy

12

N

C12N 15/19 (2006.01) A61K 38/19 (2006.01) C07H 21/00 (2006.01) C07K 14/715 (2006.01) C12N 15/62 (2006.01) C12Q 1/68 (2006.01) G01N 33/566 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2139504

The present invention relates to an isolated leukaemia inhibitory factor (LIF)-binding protein (LBP) in soluble form and obtainable from a first mammalian species, said LBP capable of inhibiting the ability of LIF from a second mammalian species to induce differentiation of M1 myeloid leukaemic cells in vitro to a greater extent when compared to its ability to inhibit LIF from said first mammalian species.

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