Leukemia-associated virus immunogen, vaccine and assay

Details Leukemia-associated virus immunogen, vaccine and assay Leukemia-associated virus immunogen, vaccine and assay

A - Human Necessities

61

K

167/129, 167/139

A61K 39/00 (2006.01) C07K 7/04 (2006.01) C07K 14/15 (2006.01) G01N 33/53 (2006.01)

Patent

CA 1265648

ABSTRACT The present invention relates to a leukemia-associated virus immunogens, vaccines, and assays. The immunogens are relatively short polypeptides with peptide sequences corresponding to the antigenic determinant domains of a leukemia-associated virus envelope protein. The immunogens when introduced into a host stimulate the production of antibodies which immunoreact with the polypeptides and the leukemia-associated virus. The immunogens may be used together with other components such as adjuvants to form immunizing compositions such as vaccines. The antibodies may be used together with other components in an assay system to detect the presence of a leukemia-associated virus antigen in a body fluid sample. The antibodies can also be used in the treatment of leukemia-associated virus infections.

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