Leukocyte-derived growth factor

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/18 (2006.01) A61K 38/18 (2006.01) C07K 14/475 (2006.01) C07K 14/52 (2006.01) C12N 1/21 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2075196

2075196 9111515 PCTABS00006 A gene encoding a leukocyte-derived growth factor (LDGF) has been isolated, cloned and sequenced. LDGF is believed to correspond to a PDGF-like monocyte-derived growth factor with chemotactic activity which is found in human wound fluid. Protease-resistant and other analogues of LDGF, as well as recombinant LDGF of native amino acid sequence, may now be produced by gene expression in transformed hosts.

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