C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/18 (2006.01) A61K 38/18 (2006.01) A61K 38/19 (2006.01) C07K 14/475 (2006.01) C07K 14/52 (2006.01) C07K 16/22 (2006.01) C07K 16/24 (2006.01) C12N 1/21 (2006.01) C12N 5/00 (2006.01) C12N 5/10 (2006.01) C12N 15/19 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2153409
A protein, Leukocyte Derived Growth Factor 2 (hereinafter LDGF2) having PDGF-like activity is described. LDGF2 reacts with PDGF receptors and processes mitogenic and/or chemotactic activity for avarious cell types, particularly connective tissue cells. LDGF2 may be used as the active ingredient in therapeutic compositions, e.g. wound healing compositions, or even further may be used as an additive to cell culture media for the purpose of stimulating cell growth. The protein has a molecular weight of about 7000 daltons determined by SDS gel electrophoresis and is about 61 amino acids in length.
Grotendorst Gary R.
Iida Naoko
Gowling Lafleur Henderson Llp
University Of South Florida
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