Leukotriene analogues

Details Leukotriene analogues Leukotriene analogues

C - Chemistry, Metallurgy

07

C

167/179, 260/518

C07C 61/35 (2006.01) C07C 57/26 (2006.01) C07C 69/743 (2006.01) C07D 295/185 (2006.01) C07F 7/18 (2006.01) C07F 9/40 (2006.01)

Patent

CA 1252111

ABSTRACT OF THE DISCLOSURE A compound of the formula Image wherein n is an integer from 2 to 4; m is an integer from 3 to 5; R is OM, OR1 or NR2R3 where M is a pharmaceutically acceptable cation; R1, R2 and R3 are the same or different and selected from the group consisting of hydrogen, C1-C2 branched, unbranched or cyclic alkyl aryl and aralkyl; or R2 and R3 taken together from a group of the formula Image can be used as an inhibitor of the lipoxygenase pathway of the arachidonic acid cascade in animals.

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