Leukotriene antagonists

Details Leukotriene antagonists Leukotriene antagonists

C - Chemistry, Metallurgy

07

C

167/179, 260/260

C07C 323/60 (2006.01) A61K 31/19 (2006.01) A61K 31/215 (2006.01) A61K 31/395 (2006.01) C07C 65/28 (2006.01) C07D 213/80 (2006.01) C07D 239/56 (2006.01) C07F 9/54 (2006.01)

Patent

CA 2021996

ABSTRACT OF THE INVENTION Leukotriene antagonists are disclosed comprising compounds having the general formula represented by the formula shown below, esters, amides and physio- logically acceptable salts thereof. These compounds retain the natural 5(S) 6(R) configuration, the 5-hydroxyl group and the natural unsaturated tail with the peptide replaced by a substituted aromatic nucleus linked via a sulfur or oxygen substituent linking a substituent to the 6 position. Image I MS #1590

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