Leukotrine-b4 derivatives, a process for the production of...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 213/30 (2006.01) C07C 59/48 (2006.01) C07C 69/732 (2006.01) C07C 69/94 (2006.01) C07C 235/42 (2006.01) C07D 213/50 (2006.01) C07D 213/55 (2006.01) C07D 213/60 (2006.01) C07D 213/64 (2006.01) C07D 213/73 (2006.01) C07D 213/81 (2006.01)

Patent

CA 2057042

ABSTRACT New leukotriene B4 analogs of Formula I Image (I), wherein R1 stands for the COOR2 radical with R2 standing for a hydrogen atom or a (C1-C4) alkyl group or R1 stands for the CH2OH radical, B stands for an alkylene group with 1-3 carbon atoms in the chain, a radical Image or a radical Image with R3 standing for a hydrogen atom, a carboxy or a methoxycarbonyl group, A stands for the groups Image , -O-, -?-, -NH-CO-, -CO-NH-, -OCH2-, -CH=CH-, -C?C-, -COCH2-, or -CHOH-CH2-, X stands for N or CH, D stands for the groups Image or Image and Image is a simple or double bond, and, optionally, the salts of these with physiologically innocuous bases, and a process for the production of these, and their pharmaceutical use.

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