Levamlodipine compound pharmaceutical composition

Details Levamlodipine compound pharmaceutical composition Levamlodipine compound pharmaceutical composition

A - Human Necessities

61

K

A61K 31/4422 (2006.01) A61K 9/20 (2006.01) A61K 9/48 (2006.01) A61K 31/4035 (2006.01) A61P 9/12 (2006.01)

Patent

CA 2754839

A levamlodipine compound pharmaceutical composition is provided, which contains levamlodipine or a pharmaceutically acceptable salt thereof, and chlorthalidone. In the present invention, levamlodipine and chlorthalidone are administrated in combination for treating hypertension, a high synergistic anti hypertensive effect is achieved, and the edema side effect due to sodium and water retention caused when levamlodipine is administrated alone is mitigated. In addition, levamlodipine increases insulin sensitivity of an organism, and resists the side effect of increase in blood glucose level caused by chlorthalidone. The pharmaceutical composition of levamlodipine and chlorthalidone overcomes the disadvantage that levamlodipine takes effects slowly in hypertension repression.

La présente invention concerne une composition pharmaceutique de composé de levoamlodipine, qui contient du levoamlodipine ou des sels pharmaceutiquement acceptables de celui-ci et de la chlortalidone. Le levoamlodipine et la chlortalidone sont utilisés en tant que combinaison pour le traitement de l'hypertension dans le cadre de la présente invention. Le levoamlodipine et la chlortalidone présentent un effet hypotensif synergique satisfaisant. En outre, les effets secondaires de l'hydropisie due à la rétention de sodium et d'eau initiée par l'utilisation de levoamlodipine seul sont améliorés. Par ailleurs, le levoamlodipine peut renforcer la sensibilité du corps à l'insuline, et résister aux effets secondaires de l'augmentation de la glycémie provoquée par la chlortalidone. La combinaison pharmaceutique de levoamlodipine et de chlortalidone permet également de surmonter l'effet de lenteur qui caractérise le levoamlodipine dans l'antihypertension.

Affiliated with

Also associated with

Rating

Levamlodipine compound pharmaceutical composition does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Levamlodipine compound pharmaceutical composition, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Levamlodipine compound pharmaceutical composition will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2064516