Lewis acid mediated synthesis of cyclic esters

C - Chemistry – Metallurgy – 07 – D

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C07D 471/02 (2006.01) C07F 9/06 (2006.01) C07F 9/28 (2006.01)

Patent

CA 2565966

Methods for the synthesis of cyclic phosphonic acid diesters from 1,3-diols are described, whereby cyclic phosphonic acid diesters are produced by reacting a chiral 1,3-diol and an activated phosphonic acid in the presence of a Lewis acid.

L'invention porte sur des méthodes de synthèse de diesters cycliques de l'acide phosphonique à partir de 1,3-diols, ces diesters cycliques de l'acide phosphonique étant obtenus par réaction d'un 1,3-diol chiral et d'un acide phosphonique activé en présence d'un acide de Lewis.

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