A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/00 (2006.01) A61K 31/70 (2006.01) A61P 35/00 (2006.01) C12N 1/15 (2006.01) C12N 1/19 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 15/09 (2006.01)
Patent
CA 2483474
The present invention provides compositions and methods for improving cancer vaccine immunogenicity using lewis Y modified mucin fused to a protein, in particular an immunoglobulin. The constructs can be produced by glycosylation of a protein, e.g. P-selectin glycoprotein ligand-1 (PSGL-1), with alpha 1,2 fucosyltransferase and alpha 1,3 fucosyltransferase.
La présente invention concerne des compositions et des procédés fournissant un vaccin immunogène anticancéreux et utilisant des protéines hybrides de mucine-immunoglobuline de Lewis Y.
Recopharma Ab
Ridout & Maybee Llp
LandOfFree
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