Ligand for herpes simplex virus entry mediator and methods...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) C07K 14/035 (2006.01) C07K 14/52 (2006.01) C07K 14/525 (2006.01) C07K 14/705 (2006.01) C07K 16/18 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) G01N 33/567 (2006.01) G01N 33/569 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2296737

A novel ligand (p30) for herpes virus entry mediator, HVEM, is provided. p30 is useful for modulating immune responses and in inhibiting infection by herpes virus. Methods for treating subjects with lymphoid cell disorders or those having or suspected of having a herpes virus infection, utilizing p30 of the invention, are also provided.

La présente invention concerne un nouveau ligand (p30) du médiateur d'accès du virus de l'herpès simplex, ou HVEM. Le p30 est utilisé pour moduler la réaction immunitaire et inhiber l'infection par le virus de l'herpès. L'invention se rapporte également à des procédés permettant de traiter avec le p30 des patients souffrant de troubles des cellules lymphoïdes ou les patients atteints, ou que l'on suppose atteints, d'une infection par le virus de l'herpès.

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