Ligand growth factors that bind to the erbb-2 receptor...

Details Ligand growth factors that bind to the erbb-2 receptor... Ligand growth factors that bind to the erbb-2 receptor...

C - Chemistry, Metallurgy

12

N

C12N 15/18 (2006.01) A61K 38/18 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61K 49/00 (2006.01) C07K 14/475 (2006.01) C07K 14/495 (2006.01) C07K 14/705 (2006.01) C07K 16/22 (2006.01) C12N 5/02 (2006.01) C12N 5/10 (2006.01) G01N 33/566 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2100549

2100549 9212174 PCTABS00014 The present invention relates to erbB-2 ligands and function derivatives thereof which are capable of binding to the erbB-2 transmembrane protein but fail to bind to epidermal growth factor receptor. The present invention further pertains to anti-ligand molecules capable of recognizing and binding to the erbB-2 ligand molecule and to screening assays for such ligands. The present invention additionally relates to uses for the erbB-2 ligand, the anti-ligand molecules and the screening assays.

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