Ligands

Details Ligands Ligands

C - Chemistry, Metallurgy

12

N

C12N 15/11 (2006.01) A61K 31/7088 (2006.01) A61K 48/00 (2006.01) A61P 31/18 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2505868

Aptamers that bind to viral envelope proteins, in particular those that bind to the envelope glycoprotein gp120 of HIV are disclosed, The use of these aptamers for screening potential therapeutic targets and in the treatment of HIV infections is also described.

L'invention concerne des aptamères qui se lient à des protéines d'enveloppe virale, notamment ceux qui se lient à la glycoprotéine gp120 d'enveloppe de HIV. L'invention concerne aussi l'utilisation de ces aptamères dans le criblage de cibles thérapeutiques potentielles et dans le traitement d'infections HIV.

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