Ligands and cationic complexes thereof with technetium 99-m

Details Ligands and cationic complexes thereof with technetium 99-m Ligands and cationic complexes thereof with technetium 99-m

C - Chemistry, Metallurgy

07

F

260/350, 260/613

C07F 9/50 (2006.01) A61K 51/04 (2006.01) C07F 9/655 (2006.01) C07F 9/72 (2006.01) C07F 13/00 (2006.01)

Patent

CA 1336437

This invention concerns novel bidentate ligands L having two phosphorus or arsenic atoms. Cationic complexes-of the ligands with Technetium-99m, e.g. having the formula [TcO2L2]+, are useful for body imaging, particularly myocardial imaging. The ligands have the general formula Y2QZQY2 where Q is phosphorus, Z is a -CC- or -CCC- or -COC- groups, the four groups Y are all C1-C8 saturated hydrocarbon or fluorohydrocarbon with 1-3 ether oxygen atoms.

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