Ligands and methods for augmenting b-cell proliferation

Details Ligands and methods for augmenting b-cell proliferation Ligands and methods for augmenting b-cell proliferation

C - Chemistry, Metallurgy

07

K

167/139, 195/1.1

C07K 14/435 (2006.01) A61K 38/17 (2006.01) A61K 47/48 (2006.01) C07K 14/54 (2006.01) C07K 14/715 (2006.01) C07K 16/18 (2006.01) C07K 16/28 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1338781

A new B-cell receptor, Bp50, a 50 kilodalton polypeptide, that functions in B-cell proliferation is described. Ligands such as lymphokines, antibody molecules or the Fv fragments of antibody molecules that bind to Bp50 and augment the proliferation of activated B-cells can be used to regulate B-cell proliferation or differentiation.

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