A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01)
Patent
CA 2568428
Antibodies or other ligands specific for the binary uPA-uPAR complexes, for ternary complexes comprising uPA-uPAR and for complexes of uPAR and proteins other than uPA such as integrins inhibit the interaction of uPA and uPAR with additional molecules with which the complexed interact. Such antibodies or other ligands are used in diagnostic and therapeutic methods, particularly against cancer.
L'invention concerne des anticorps et autres ligands spécifiques des complexes binaires uPA-uPAR, des complexes ternaires comprenant uPA-uPAR, et des complexes d'uPAR et de protéines autres que uPA, tels que les intégrines, qui inhibent l'interaction d'uPA et d'uPAR avec des molécules additionnelles avec lesquelles les complexes interagissent. Ces anticorps et autres ligands sont utilisés dans des méthodes diagnostiques ou thérapeutiques, notamment contre le cancer.
Mazar Andrew P.
Parry Graham C.
Attenuon Llc
Smart & Biggar
LandOfFree
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