Ligands for transition-metal-catalyzed cross-couplings, and...

Details Ligands for transition-metal-catalyzed cross-couplings, and... Ligands for transition-metal-catalyzed cross-couplings, and...

C - Chemistry, Metallurgy

07

F

C07F 9/02 (2006.01)

Patent

CA 2708369

Ligands for transition metals are disclosed herein, which may be used in various transition-metal-catalyzed carbon-heteroatom and carbon-carbon bond-forming reactions. The disclosed methods provide improvements in many features of the transition-metal-catalyzed reactions, including the range of suitable substrates, number of catalyst turnovers, reaction conditions, and efficiency. For example, improvements have been realized in transition- metal-catalyzed cross-coupling reactions.

L'invention concerne des ligands pour des métaux de transition, lesquels peuvent être utilisés dans diverses réactions formant des liaisons carbone-carbone et carbone-hétéroatome catalysées par un métal de transition. Les procédés de la présente invention permettent des améliorations de nombreuses caractéristiques des réactions catalysées par un métal de transition, dont la gamme de substrats appropriés, le nombre de rotations du catalyseur, les conditions de réaction et le rendement. Par exemple, des améliorations ont été réalisées dans des réactions de couplage croisé catalysées par un métal de transition.

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