C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 65/105 (2006.01) A61K 31/185 (2006.01) A61P 25/00 (2006.01) C07C 65/40 (2006.01) C07C 69/94 (2006.01) C07D 263/57 (2006.01) C07D 277/66 (2006.01) C07D 307/80 (2006.01) C07D 333/16 (2006.01) C07D 333/24 (2006.01) C07D 333/56 (2006.01) C07D 333/60 (2006.01)
Patent
CA 2511178
Compounds which have utility in the treatment of conditions associated with altered mitochondrial function. The compounds having structure (I), including stereoisomers, prodrugs, and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5 and R6 are as defined herein. Pharmaceutical compositions containing a compound of structure (I), as well as methods relating to the use thereof, are also disclosed.
L'invention concerne des composés présentant une utilité dans le traitement d'états pathologiques associés à une fonction mitochondriale modifiée. Elle concerne notamment des composés de structure (I), y compris des stéréoisomères, des promédicaments et des sels pharmaceutiquement acceptables desdits composés. Dans cette structure, R¿1?, R¿2?, R¿3?, R¿4?, R¿5? et R¿6? sont tels que définis dans la description. L'invention concerne en outre des compositions pharmaceutiques contenant un composé de structure (I), ainsi que des méthodes associées à leur utilisation.
Ahlijanian Michael K.
Ghosh Soumitra S.
Liras Spiros J.
Pei Yazhong
Tang Xiao-Qing
Borden Ladner Gervais Llp
Migenix Corp.
Pfizer Inc.
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