Ligands of melanocortin receptors

Details Ligands of melanocortin receptors Ligands of melanocortin receptors

C - Chemistry, Metallurgy

07

K

C07K 14/665 (2006.01) A61K 38/16 (2006.01) A61K 38/22 (2006.01) C07K 7/08 (2006.01) C07K 7/64 (2006.01) C07K 14/68 (2006.01) C07K 14/72 (2006.01)

Patent

CA 2614678

The present invention is directed to a compound according to formula, (R2R3)- B1-A1-c(A2-A3-A4-A5-A6-A7-A8-A9)-A10-A11-A12-A13-B2-B3-R1, that act as ligands for one or more of the melanocortin receptors, the pharmaceutically- acceptable salts thereof, to methods of using such peptides to treat mammals and to pharmaceutical compositions useful therefore comprising said peptides.

L'invention concerne un composé de la formule, (R2R3)-B1-A1-c(A2-A3-A4-A5-A6-A7-A8-A9)-A10-A11-A12-A13-B2-B3-R1, qui agit comme ligands d'un ou de plusieurs récepteurs de la mélanocortine, et de leurs sels pharmaceutiquement acceptables. Elle concerne également les procédés d'utilisation de ces peptides dans le traitement de mammifères ainsi que des compositions pharmaceutiques utilisées à cet effet qui renferment lesdits peptides.

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