Linear and cyclic analoques of alpha-msh fragments with...

C - Chemistry – Metallurgy – 07 – K

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167/101, 150/13,

C07K 7/54 (2006.01) A61K 38/12 (2006.01) A61K 38/34 (2006.01) A61K 51/08 (2006.01) C07K 14/685 (2006.01) G01N 33/574 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1340107

The present invention relates to linear and cyclic Alpha-MSH fragment analogues of Ac-Nle4 - Glu5 - His6 -D- Phe7 - Arg8 - Trp9 - Gly10 - NH2. The method of stimulating melanocytes by topical and other modes of application of these biologically-active analogues and compositions comprising these analogues for use in the method are disclosed.

578920

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