Linear polyesteramides from aminophenolic esters

Details Linear polyesteramides from aminophenolic esters Linear polyesteramides from aminophenolic esters

C - Chemistry, Metallurgy

08

G

C08G 69/44 (2006.01) A61K 47/34 (2006.01) A61L 31/06 (2006.01) A61L 31/10 (2006.01) A61L 31/14 (2006.01) C08L 77/12 (2006.01)

Patent

CA 2737769

The present invention is directed to linear, biodegradable polyesteramide (PEA) polymers synthesized with repeating units derived from aminophenol esters and diacids. These PEAs have a monomer repeat represented by the following formula; as well as a variety of uses to coat, form or comprise medical devices, combination medical devices and pharmaceutical compositions, including sustained release formulations.

La présente invention concerne des polymères, en l'occurrence des polyesteramides (PEA) linéaires biodégradables synthétisés portant des unités récurrentes dérivées d'aminophénol esters et de diacides. Ces polyesteramides comportent un monomère récurrent représenté par la formule jointe. L'invention concerne également diverses utilisations et notamment l'association par enrobage, constitution ou inclusion, à des dispositifs médicaux, des dispositifs médicaux combinés et de compositions pharmaceutiques, y-compris des formulations à libération prolongée.

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