Linkers

Details Linkers Linkers

C - Chemistry, Metallurgy

07

K

C07K 14/52 (2006.01) C12N 15/62 (2006.01)

Patent

CA 2575441

We disclose therapeutic polypeptides comprising at least two domains capable of binding to a cytokine receptor, wherein the domains are connected by a peptide linker, wherein the linker optionally comprises a rigid alpha helical region.

L'invention concerne des polypeptides thérapeutiques comprenant au moins deux domaines capables de se lier à un récepteur de cytokine, les domaines étant connectés par un lieur peptide, le lieur comprenant, facultativement, une région hélicoïdale alpha rigide.

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