Linking gene sequence to gene function by three dimensional...

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/68 (2006.01) C07K 14/00 (2006.01) C12N 15/09 (2006.01) C12P 19/34 (2006.01) G01N 33/48 (2006.01) G01N 33/68 (2006.01) G01N 37/00 (2006.01) G06F 17/00 (2006.01) G06F 17/30 (2006.01) G06F 19/00 (2006.01)

Patent

CA 2337153

The present invention provides a structure-functional analysis engine for the high-throughput determination of the biochemical function of protein domains of unknown function, as exemplified in the flowchart of the figure. The present invention uses bioinformatics, molecular biology and nuclear magnetic resonance tools for the rapid and automated determination of the three- dimensional structures of proteins and protein domains.

L'invention concerne un moteur d'analyse fonctionnelle de structure qui est destiné à la détermination à haut débit de la fonction biochimique de domaines de protéines dont la fonction est inconnue, selon l'exemple illustré dans l'organigramme de la figure. La présente invention utilise la bio-informatique, la biologie moléculaire et des instruments de résonance magnétique nucléaire à des fins de détermination rapide et automatisée des structures tridimensionnelles de protéines et de domaines de protéines.

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