Lipase activity determining reagent

Details Lipase activity determining reagent Lipase activity determining reagent

C - Chemistry, Metallurgy

12

Q

150/3.2, 150/15.

C12Q 1/44 (2006.01)

Patent

CA 1041409

Abstract of the Disclosure: A diagnostic kit is described for determining lipase activity, which comprises as the active ingredient one of the S-acyl compounds of the formula: Image Image Image or Image wherein n is an integer of 2 to 4, inclusive; n' is an integer of 2 to 4, inclusive or of 9 to 13, inclusive; m is an integer of 3, 7 or 11; m' is an integer of 4 or 12; y is an integer of 1 or 2; X is sulfur atom or oxygen atom; Y is sulfur atom, oxygen atom or ethylene group; provided that when y is 1, m' is 4 and when y is 2, m' is 12. Also described is a method for determining lipase activity by reacting the S-acyle compound with lipase in a buffer solution containing a chromogenic sulfhydryl reagent and then subjecting the resultant to colorimetry. - 1 -

227946

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