Lipase inhibiting composition

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/44 (2006.01) A61K 8/42 (2006.01) A61K 8/49 (2006.01) A61K 8/55 (2006.01) A61K 8/96 (2006.01) A61Q 5/00 (2006.01)

Patent

CA 2486381

The invention relates to compositions for treating dandruff comprising compounds that are non-polymeric and/or have a weight average molecular weight of less than about 1000. These compounds, when used at a concentration of about 0.001% or less, inhibit the activity of any Malassezia globosa lipase by at least 50%. The invention also relates to the use of these compounds for inhibiting lipase activity.

L'invention concerne des compostions destinées à traiter des pellicules contenant des composés non polymères et/ou possédant une masse moléculaire moyenne en poids inférieure à environ 1000. Ces composés inhibent l'activité de toute lipase <i>Malassezia globosa</i> d'au moins 50 %, lorsqu'ils sont utilisés dans une concentration d'environ 0,001 % ou moins. Cette invention concerne également l'utilisation de ces composés en vue d'inhiber l'activité des lipases.

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