Lipase inhibitors

Details Lipase inhibitors Lipase inhibitors

C - Chemistry, Metallurgy

07

F

C07F 5/02 (2006.01) A61K 31/69 (2006.01) A61P 3/06 (2006.01)

Patent

CA 2586479

The present invention relates to inhibitors of lipases, such as inhibitors of endothelial lipase, as well as pharmaceutical compositions thereof, and methods for using such inhibitors. The prototype of these inhibitors has lipophilic portion and an electrophilic site.

La présente invention concerne des inhibiteurs de lipases, par exemple des inhibiteurs d'une lipase endothéliale, ainsi que des compositions pharmaceutiques et des méthodes d'utilisation desdits inhibiteurs. Le prototype de ces inhibiteurs comprend une partie lipophile et un site électrophile.

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