Lipase variants

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/55 (2006.01) C11D 3/386 (2006.01) C12N 9/16 (2006.01) C12N 9/20 (2006.01) C12N 15/09 (2006.01) C12Q 1/44 (2006.01)

Patent

CA 2432329

Attaching a peptide extension to the C-terminal amino acid of a lipase re- duces the tendency to form odor. This may lead to lipase variants with a reduced odor generation when washing textile soiled with fat which includes relatively short-chain fatty acyl groups (e.g. up to C8) such as dairy stains containing butter fat or tropical oils such as coconut oil or palm kernel oil.

La fixation d'une prolongation peptidique à l'acide aminé de terminaison C d'une lipase limite la tendance à générer une odeur. Ceci permet d'obtenir des variantes de lipase ne générant qu'un niveau limité d'odeur quand on lave des textiles salis par de la graisse contenant des groupes d'acyle gras à chaîne relativement courte (par exemple, C¿8? Maximum), par exemple, des taches contenant des graisses de produits laitiers ou des huiles tropicales, telles que l'huile de noix de coco ou l'huile de palme.

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