A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 48/00 (2006.01) C07H 21/04 (2006.01) C07K 14/245 (2006.01) C07K 16/12 (2006.01) C12N 1/21 (2006.01) C12N 9/12 (2006.01) C12N 15/00 (2006.01) C12N 15/31 (2006.01) C12N 15/52 (2006.01) C12N 15/54 (2006.01) C12N 15/70 (2006.01)
Patent
CA 2290809
The present invention relates, in general, to lipid A 4' kinase and, in particular, to a nucleic acid encoding lipid A 4' kinase and to a method of producing lipid A 4' kinase recombinantly using same. The invention further relates to methods of producing 4' phosphorylated lipid A analogs using the recombinantly produced lipid A 4' kinase.
La présente invention se rapporte, en général, à la lipide-A-4'-kinase et, en particulier à un acide nucléique codant pour cette lipide-A-4'-kinase, et à un procédé permettant de produire la lipide-A-4'-kinase par recombinaison à l'aide de celui-ci. L'invention concerne également des procédés de fabrication d'analogues 4'-phosphorylés du lipide-A à l'aide de la lipide-A-4-'-kinase produite par recombinaison.
Garrett Teresa A.
Kadrmas Julie L.
Raetz Christian R. H.
Duke University
Goudreau Gage Dubuc
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