Lipid a analog/immunogenic carrier conjugates, the use...

Details Lipid a analog/immunogenic carrier conjugates, the use... Lipid a analog/immunogenic carrier conjugates, the use...

A - Human Necessities

61

K

A61K 39/116 (2006.01) A61K 39/02 (2006.01) A61K 39/385 (2006.01) A61K 39/40 (2006.01) C07H 13/04 (2006.01) C07H 13/06 (2006.01) C07H 15/04 (2006.01) C07K 1/107 (2006.01) C07K 14/21 (2006.01) C07K 14/31 (2006.01) C07K 14/34 (2006.01) C12P 19/44 (2006.01)

Patent

CA 2105965

2105965 9216230 PCTABS00016 The invention relates to lipid A analog/immunogenic carrier conjugates and the use thereof as vaccines for the prophylaxis of septic shock in animals. The invention provides for a polyvalent vaccine which contains the lipid A analog/immunogenic carrier conjugate. The invention also relates to a polyvalent hyperimmune gammaglobulin comprising an effective neutralizing amount of an anti-lipid A gammaglobulin and an effective opsonizing amount of an O antigen specific gammaglobulin. Kits containing these materials are also provided.

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