Lipid-a analogs: new monosaccharide and dissaccharide...

C - Chemistry – Metallurgy – 07 – H

Patent

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C07H 15/04 (2006.01) A61K 39/02 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) C07H 13/06 (2006.01) C07K 16/12 (2006.01) C12N 9/14 (2006.01) C12N 15/13 (2006.01) C12N 15/55 (2006.01) C12P 21/08 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2126341

2126341 9319761 PCTABS00027 Compounds are disclosed that are useful for eliciting antibodies which bind to Lipid-A, induce protective immunity against gram-negative bacterial infection, protect against viral infection, control tumor growth, and bind to receptors in competition with Lipid-A. Compositions containing these compounds are also disclosed. Further, antibodies elicited by the compounds are disclosed, as well as uses for such antibodies, for instance in treating septicemia.

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