Lipid a composition as immunogenic agents to prevent or...

A - Human Necessities – 61 – K

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A61K 39/40 (2006.01) A61K 9/127 (2006.01) A61K 9/50 (2006.01) A61K 9/52 (2006.01) A61K 31/575 (2006.01) A61K 39/02 (2006.01) A61K 39/385 (2006.01) A61M 1/38 (2006.01) C07K 16/12 (2006.01) G01N 33/92 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2094588

LIPID A COMPOSITION AS IMMUNOGENIC AGENTS TO PREVENT OR TREAT GRAM-NEGATIVE BACTERIAL INFECTIONS ABSTRACT This invention is directed to the production of antibodies against lipid A by using encapsulating slow-releasing delivery materials or devices containing concentrations of lipid A that are greater than could be given safely to humans in the absence of said materials or devices. The antibodies to lipid A can be used for binding the antibodies to the lipid A that is present in the lipopolysaccharide that coats the surface of the Gram-negative bacteria.

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