A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/107 (2006.01) A61K 9/48 (2006.01) A61K 47/44 (2006.01)
Patent
CA 2401889
The invention refers to a lipid carrier composition for controlled release of a bioactive substance, which comprises at least one triglyceride oil, and at least one polar lipid selected from the group consisting of phosphatidylethanolamine and monohexosylceramide, and ethanol, which is charactrised in that the carrier composition has the ability to form a cohesive structure, which structure is retained in an aqueous environment. The invention also refers to a pharmaceutical composition consisting of said lipid carrier and a bioactive substance dissolved or dispersed in the carrier, preferably an injectable composition.
L'invention se rapporte à un excipient liquide permettant la libération contrôlée d'une substance bioactive, qui comporte au moins une huile triglycéride et au moins un liquide polaire sélectionné dans le groupe constitué de la phosphatidyléthanolamine et du monohexosylcéramide, et de l'éthanol. Cet excipient liquide se caractérise en ce que sa composition lui permet de former une structure cohésive qui est retenue dans un environnement aqueux. L'invention se rapporte également à une composition pharmaceutique composée dudit excipient liquide et d'une substance bioactive dissoute ou dispersée dans ledit excipient, de préférence une composition injectable.
Adde Christina
Fischer Andreas
Herslof Bengt
Lipocore Holding Ab
Mccarthy Tetrault Llp
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