Lipid carrier compositions with enhanced blood stability

Details Lipid carrier compositions with enhanced blood stability Lipid carrier compositions with enhanced blood stability

A - Human Necessities

61

K

A61K 9/127 (2006.01) A61K 9/00 (2006.01)

Patent

CA 2467064

Liposomes that contain at least 10 mol % of a negatively charged lipid coupled to an non-zwitterionic moiety are stable in the blood. Liposomes containing at least 1 mol % of such lipids may be frozen safely.

Les liposomes qui contiennent au moins 10 % molaire d'un lipide à charge négative couplé à une fraction non zwitterionique se comportent de façon stable dans le sang. Les liposomes contenant moins de 1 % molaire de tels lipides peuvent être congelés sans risque.

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