Lipid-containing compositions and uses thereof

A - Human Necessities – 61 – K

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Details

A61K 9/107 (2006.01) A61K 9/127 (2006.01) A61K 47/24 (2006.01) A61K 47/32 (2006.01) A61K 47/44 (2006.01) A61P 11/00 (2006.01) A61K 9/00 (2006.01)

Patent

CA 2301711

Lipid-containing compositions are disclosed which provide surfactants and solubilising agents useful in medicine, biochemistry and other industries. The compositions comprise a membrane-forming polar lipid and a synthetic amphipathic polymer containing hydrophobic and anionic hydrophilic groups which preferably are evenly arranged along a linear backbone. In some embodiments the polymer is a copolymer, for example poly(maleic acid styrene) (PMAS), in which first and second monomer units are arranged in alternating relationship along its length.

L'invention concerne des compositions contenant des lipides. Ces compositions servent de tensioactifs et d'agents de solubilisation utiles en médecine, en biochimie et dans d'autres industries. Ces compositions comprennent un lipide polaire formateur de membrane et un polymère amphipathique synthétique contenant des groupes hydrophobes et des groupes anioniques hydrophiles qui sont de préférence disposés sur la longueur d'une chaîne principale. Dans certains modes de réalisation, le polymère et un copolymère, par exemple le poly(styrène d'acide maléique) (PMAS) dans lequel le premier et le second motif monomère sont disposés en alternance sur la longueur de la chaîne.

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