A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/127 (2006.01)
Patent
CA 2426244
The present invention provides lipid-based systemic delivery vehicles and method for selectively targeting an active agent to a specific tissue site. The methods include designing a lipid-based systemic delivery vehicle having a plurality of constitutent parts, and thereafter varying the amounts of each of the plurality of constituent parts to impart tissue selectivity. After tissue selectivity is imparted it is possible to selectively target an active agent to a specific tissue site.
L'invention concerne des véhicules et des procédés d'administration systémique à base lipide pour le ciblage sélectif d'un agent actif vers un site tissulaire spécifique. Les procédés consistent à mettre au point un véhicule d'administration systémique à base lipide ayant une pluralité d'éléments constitutifs, pour, ensuite, varier les quantités de chaque pluralité d'éléments constitutifs afin de procéder à l'administration sélective aux tissus. Après cette administration sélective aux tissus, il est possible de faire un ciblage sélectif d'un agent actif vers un site tissulaire spécifique.
Cullis Pieter R.
Fenske David B.
Maclachlan Ian
Fetherstonhaugh & Co.
Inex Pharmaceuticals Corporation
The University Of British Columbia
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