B - Operations – Transporting – 01 – J
Patent
B - Operations, Transporting
01
J
B01J 13/06 (2006.01) A61K 9/51 (2006.01) B01F 17/00 (2006.01)
Patent
CA 2401766
The invention concerns nanocapsules, in particular with an average size less than 50 nm, consisting of an essentially lipid core liquid or semiliquid at room temperature, coated with an essentially lipid film solid at room temperature having a thickness of 2 - 10 nm. The invention also concerns a method for preparing same which consists in producing a reverse phase of an aqueous emulsion brought about by several temperature raising and lowering cycles. Said lipid nanocapsules are particularly designed for producing a medicine.
La présente invention concerne des nanocapsules, en particulier de taille moyenne inférieure à 50 nm, constituées d'un coeur essentiellement lipidique liquide ou semi-liquide à température ambiante, enrobé d'un film essentiellement lipidique solide à température ambiante d'épaisseur 2 - 10 nm. Elle concerne également un procédé pour leur préparation qui consiste en l'inversion de phase d'une émulsion huile/eau provoquée par plusieurs cycles de montée et de descente en température. Les nanocapsules lipidiques de l'invention sont particulièrement destinées à la fabrication d'un médicament.
Benoit Jean-Pierre
Heurtault Beatrice
Pech Brigitte
Proust Jacques-Emile
Richard Joel
Mainelab
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Universite D'angers
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