Lipidated glycosaminoglycan particles and their use in drug...

Details Lipidated glycosaminoglycan particles and their use in drug... Lipidated glycosaminoglycan particles and their use in drug...

A - Human Necessities

61

K

A61K 9/14 (2006.01) A61K 9/00 (2006.01) A61K 9/16 (2006.01) A61K 9/51 (2006.01) A61K 47/48 (2006.01)

Patent

CA 2456966

Lipidated glycosaminoglycan particles are prepared by reacting a glycosaminoglycan with at least one lipid to cross-link the carboxylic acid groups in the glycosaiminoglycan with a primary amine in the lipid. These particles can be used to encapsulate active ingredients, such as drugs for use in the treatment of pathological conditions in an animal.

On prépare des particules de glycosaminoglycane en faisant réagir un glycosaminoglycane avec au moins un lipide de façon à réticuler les groupes d'acide carboxylique présents dans ce glycosaminoglycane avec un amine primaire de ce lipide. Ces particules conviennent pour encapsuler des principes actifs, tels que des médicaments destinés au traitement d'états pathologiques d'un animal.

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