Lipids, their production and use

C - Chemistry – Metallurgy – 07 – D

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C07D 401/12 (2006.01) C07C 317/18 (2006.01) C07C 321/12 (2006.01) C07D 213/48 (2006.01) C07D 213/55 (2006.01) C07D 239/34 (2006.01) C07D 403/12 (2006.01) C07D 417/12 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2001532

ABSTRACT Lipid derivatives represented by the formula: Image wherein R1 stands for an optionally substituted higher alkyl group, R2 stands for an optionally substituted lower alkyl group or an optionally substituted nitrogen-containing heterocyclic group, R3 stands for a tertiary amino group or a quaternary ammonium group, J stands for oxygen atom or S(O)t (where t denotes 0, 1 or 2), m and n respectively denotes 1 or 2, p denotes 0, 1 or 2, q and r respectively denote an integer of 2 to 5, and salts thereof have antitumor activities including differentiation-inducing activity and are useful as antitumor agents.

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