A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/50 (2006.01) A23L 1/30 (2006.01) A61K 31/385 (2006.01)
Patent
CA 2653403
Lipoic acid pellets are described, obtained from inert cores externally coated with lipoic acid. The so obtained active cores are coated with a first layer of insulating polymeric material and then with a polymeric coat that is insoluble at the gastric pH. Pellet are then formulated pharmaceutically, for instance in jelly capsules or controlled release capsules or as oral suspensions, dispersible powders, sachets, etc.
La présente invention porte sur des granules d'acide lipoïque obtenus à partir de noyaux inertes dont la surface extérieure est revêtue d'acide lipoïque. Les noyaux actifs ainsi obtenus sont revêtus d'une première couche de matériau polymère d'isolation, puis d'un revêtement polymère insoluble au pH gastrique. Les granules sont ensuite formulés en une forme galénique, par exemple des capsules de gélatine ou des capsules à libération contrôlée, ou sous forme de suspensions orales, de poudres dispersibles, de sachets, etc.
Boltri Luigi
Fabiani Flavio
Magri' Paolo
Mapelli Luigi
Nardi Antonio
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Eurand Pharmaceuticals Limited
Laboratorio Chimico Internazionale S.p.a.
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