Lipomatrix preparation

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/127 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2318556

The invention describes a Lipomatrix composed of lipid lattices of stacked bilayers which, when hydrated, form liposomes. The invention also provides a simplified method used to generate highly effective liposomal preparations. Vaccine compositions having superior immunological properties use biomedical- grade liposomes which can be produced from a Lipomatrix, using safe and efficient methods. Use of the inventive methods produces highly potent vaccines against tumor antigens.

La présente invention concerne une lipomatrice composée de réseaux lipidiques à doubles couches empilées qui forment des liposomes lorsqu'elles sont hydratées, et un procédé simplifié permettant de fabriquer des préparations de liposomes à haute efficacité. L'invention se rapporte en outre à des compositions de vaccin dotées de propriétés immunologiques supérieures, dans lesquelles sont utilisés des liposomes biomédicaux obtenus à partir d'une lipomatrice selon des procédés sûrs et efficaces. L'utilisation des procédés de l'invention permet de produire des vaccins extrêmement actifs contre les antigènes tumoraux.

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