Lipopeptides from actinoplanes sp. with pharmacological...

C - Chemistry – Metallurgy – 12 – P

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C12P 21/04 (2006.01) A61K 38/12 (2006.01) C07K 7/60 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2125376

Lipopeptides from Actinoplanes sp. with pharmacological action, process for their production and the use thereof The invention relates to lipopeptides with very homologous amino-acid sequences but different fatty acid residues (lipid portion) which are synthesized by Actino-planes sp. during fermentation and are released into the culture medium, to a process for isolating the lipopeptides from the culture medium cad purifying theme, to the use of the lipopeptides as pharmacologically active substances, in particular against Gram-positive bacteria, and to Actinoplaaes sp. DSM 7358 for producing the abovementioned lipopeptides.

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