Lipopeptides inducing t lymphocytic cytotoxicity bearing at...

Details Lipopeptides inducing t lymphocytic cytotoxicity bearing at... Lipopeptides inducing t lymphocytic cytotoxicity bearing at...

C - Chemistry, Metallurgy

07

K

C07K 14/025 (2006.01) A61K 39/295 (2006.01) A61K 47/48 (2006.01) C07K 14/16 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2328294

The invention concerns lipopeptides comprising at least one auxiliary T epitope, at least one CTL epitope and at least a lipid residue, characterised in that the epitopes and the lipid part, and the epitopes are independently separated by amino acids, called spacers, comprising amino acid chains charged in neutral medium, ensuring affinity for water of said lipopeptides. The invention also concerns the use of said lipopeptides for inducing an immune response against HIV and BHV, papillo mavirus, melanoma p-53, or malaria.

Lipopeptides comprenant au moins un épitope T auxiliaire, au moins un épitope CTL et au moins un résidu lipidique, caractérisés en ce que les épitopes et la partie lipidique d'une part, et les épitopes d'autre part, sont séparés indépendamment par des séquences d'acides aminés, appelées espaceurs, comprenant des enchaînements d'acides aminés globalement chargés en milieu neutre, assurant l'hydrophilie de ces lipopeptides. Utilisation de ces lipopeptides pour l'induction d'une réponse immunitaire à l'encontre du VIH, du VHB, du papillomavirus, de la p-53 du mélanome, ou de la malaria.

Affiliated with

Also associated with

Rating

Lipopeptides inducing t lymphocytic cytotoxicity bearing at... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Lipopeptides inducing t lymphocytic cytotoxicity bearing at..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Lipopeptides inducing t lymphocytic cytotoxicity bearing at... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1680921