Lipophilic binary systems for the administration of...

A - Human Necessities – 61 – K

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A61K 9/107 (2006.01) A61K 9/48 (2006.01) A61K 38/13 (2006.01)

Patent

CA 2283780

Binary pharmaceutical formulations comprising (i) a cyclosporine compound, (ii) a lipophilic phase and (iii) a surfactant provide bioavailability of the active ingredient which is equivalent to that provided by ternary compositions, but without the need for a hydrophilic phase.

L'invention concerne des préparations pharmaceutiques binaires comprenant (i) un composé de cyclosporine, (ii) une phase lipophile et (iii) un tensio-actif. Ces préparations assurent une biodisponibilité du composant actif équivalente à celle assurée par des compositions ternaires mais sans nécessiter de phase hydrophile.

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