Lipophilic electrophoretic probes

Details Lipophilic electrophoretic probes Lipophilic electrophoretic probes

C - Chemistry, Metallurgy

07

C

C07C 321/20 (2006.01) A61B 1/00 (2006.01) G01N 27/447 (2006.01) G01N 33/58 (2006.01)

Patent

CA 2493671

Compounds, compositions, and methods for labeling membranes are disclosed. Compounds of formula G-L-E are described wherein G is a lipophilic group, L is a cleavable linkage and E is an electrophoretic group. the compounds become associated with membranes, and can be cleaved with a cleavage-inducing moiety thereby releasing the detectable electrophoretic group.

L'invention concerne des composés, des compositions et des méthodes de marquage de membranes. Elle concerne notamment des composés de formule G-L-E, dans laquelle G est un groupe lipophile, L est une liaison clivable et E est un groupe électrophorétique. Ces composés s'associent à des membranes et peuvent être clivés avec une fraction induisant un clivage, d'où la libération du groupe électrophorétique détectable.

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