Lipopolyamines, their preparation and their use

Details Lipopolyamines, their preparation and their use Lipopolyamines, their preparation and their use

C - Chemistry, Metallurgy

07

C

530/5.06, 195/1.

C07C 237/22 (2006.01) C07F 9/10 (2006.01) C07K 5/02 (2006.01) C12N 1/00 (2006.01) C12N 5/10 (2006.01)

Patent

CA 2014518

Nouvelles lipopolyamines de formule générale (I), leurs sels, leur préparation et leur emploi. (voir formule I) n = 1 à 5 et m = 2 à 6 R représente un radical (voir formule II) (R1 et R2 : radical aliphatique contenant 12 à 22 atomes de carbone ; R : atome d'hydrogène ou radical alkyle éventuellement substitué par phényle), ou un radical (voir formule III) (X = CH2, CO ; R3 et R4 radical aliphatique contenant 11 à 21 atomes de carbone), leur préparation et leur emploi. Les lipopolyamines de formule générale (I) sont particulièrement utiles comme vecteurs de transfection de cellules eucaryotes.

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