Liposomal influenza vaccine composition and method

Details Liposomal influenza vaccine composition and method Liposomal influenza vaccine composition and method

A - Human Necessities

61

K

A61K 39/145 (2006.01) A61K 9/127 (2006.01) A61K 39/39 (2006.01)

Patent

CA 2258878

Subunit influenza vaccines containing an influenza H/N antigen and a cytokine immunopotentiator, where at least one and preferably both are encapsulated in liposomes, are described. The vaccines stimulate a strong humoral and CTL response. Also described are methods of immunization using such vaccines.

L'invention concerne des vaccins de sous-unité contre la grippe, contenant un antigène H/N et un immuno-stimulateur de cytokine, dans lesquels au moins l'un des deux composants et de préférence les deux est (sont) encapsulé(s) dans des liposomes. Ces vaccins stimulent une réaction forte de la cellule T cytotoxique et humorale. L'invention concerne également des procédés d'immunisation effectuée à l'aide de ces vaccins.

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